Important genetic differences in how females and males experience depression have been revealed for the first time in findings that could pave the way for more targeted interventions and treatments.
In the study, published in Nature Communications, scientists found that genetic factors contribute more to depression risk in females than in males. The team discovered about twice as many genetic "flags" for depression in the DNA of females as they did in that of males.
Seeking commentary, including:
What should doctors consider about these differences when treating women versus men?
posted10/13/2025
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published10/18/2025
Recently published by Healthgrades
Psychiatrist: Genetic differences in how women/men experience depression
Important genetic differences in how females and males experience depression have been revealed for the first time in findings that could pave the way for more targeted interventions and treatments.
In the study, published in Nature Communications, scientists found that genetic factors contribute more to depression risk in females than in males. The team discovered about twice as many genetic "flags" for depression in the DNA of females as they did in that of males.
Seeking commentary, including:
What should doctors consider about these differences when treating women versus men?